Gwyneth Paltrow's blog Goop is one of my favorites. She just did a special on San Francisco hot spots and she, along with the Turlington sisters, nailed it. Seriously she included everything, even my favorite nail spot, Teashi. http://goop.com/newsletter/92/en/
Check out the blog above and the list that follows. The only thing she left out was:
1) Sam's Cafe in Tiburon- either take the ferry over from SF or rent a car and drive over the GG bridge about 20 mins and head over to Sam's for a crab sandwich and bloody mary brunch
2) Kokkari-best greek food in town
3) Hiking Tennesse Valley-perfect 3 mile hike through valley's, past wildflowers and eventually to a sand beach and the ocean
4) Rose's Cafe- Best Breakfast place in Cow Hollow right by the Marina. They have the most amazing breakfast pizza and coffee served in huge bowls.
Love, love, love.